Professor Bice Fubini
Professor of General and Inorganic Chemistry
Dipartimento di Chimica IFM (Chimica Inorganica, Fisica e dei Materiali)
Bice Fubini’s research focuses on solid and surface chemistry, particle toxicology, chemical bases in the health effects of mineral dusts, and nanotoxicology. Professor Fubini is an expert on the relationships between surface characteristics, biological responses and toxicity of particulates including asbestos and silica polymorphs. Claire Horwell has collaborated with Bice Fubini's group to study, for the first time, the generation of free and surface radicals from volcanic ash.
Professor Fubini has developed studies on the chemical basis of the toxicity of solid materials, mainly inhaled particles, and is currently the Head of the Interdepartmental Center “G.Scansetti” for Studies on Asbestos and other Toxic Particulates, which coordinates research & formation activities carried out in a large spectrum of departments, form earth sciences to occupational medicine and epidemiology.
In 1997 and 2001 Professor Fubini was a member of two working groups on IARC Monographs on the evaluation of carcinogenic risks to humans: Silica, some silicates, coal dust and para-aramid fibrils (1997); and man-made vitreous fibres (2001). In 1997 she organized, chaired and directed a workshop on the use of "Non-animal tests for Evaluating the Toxicity of Solid Xenobiotics" ECVAM (European Centre for the Validation of Alternative Methods).
Horwell C.J., Fenoglio, I., & Fublni, B. (2007) 'Iron-induced hydroxyl radical generation from basaltic volcanic ash', Earth and Planetary Science Letters, 261(3-4), 662-669.
Horwell, C.J., Fenoglio, I., Ragnarsdottir, K.V., Sparks, R.S.J., and Fubini, B. (2003) ‘Surface reactivity of volcanic ash from the eruption of Soufrière Hills volcano, Montserrat, with implications for health hazards’, Environmental Research, 93(2): 202-215.
Fenoglio, I., Prandi, L., Tomatis, M. and Fubini, B. (2001) ’Free Radical Generation in the Toxicity of Inhaled Mineral Particles: the Role of Iron Speciation at the Surface of Asbestos and Silica’, Redox Rep. 6, 235-241.
Fubini, B, Fenoglio, I., Elias, Z. and Poirot, O. (2001) ‘On the Variability of the Biological Responses to Silicas: Effect of Origin, Crystallinity and State of the Surface on the Generation of Reactive Oxygen Species and Consequent Morphological Transformations in Cells’, Journal of Environmental Pathology Toxicology and Oncology, 20, 87-100.
Fubini, B., Zanetti, G., Altilia, S., Tiozzo, R., Lison, D. and Saffiotti, U. (1999) ‘Relationship between surface properties and cellular responses to crystalline silica: studies on heat-treated cristobalite’, Chem. Res. Toxicol., 12, 737-745.
Fubini, B. and Otero-Aréan, C., (1999) ‘Chemical aspects of the toxicity of inhaled mineral dusts’, Chem. Soc. Rev., 28, 373-381.
Fubini, B. (1998) ‘Health effect of silica’, in The surface properties of silicas (Legrand J.P. ed) chap 5, pp 415-464, J. Wiley and Sons, Chichester.
Download our pamphlets on preparing for ashfall and on the health hazards of ash. They are designed for mass distribution at the onset of new eruptions. They are now avaiable in English, Japanese, French Spanish, Portuguese, Swahili, Indonesian and Icelandic with Italian versions being available shortly. Please see our Pamphlets page for further infomation.